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ISB is working to leverage systems biology approaches to understand the mechanistic links among the processes that accompany and/or lead to aging. Learn more COVID-19 Immune Response Study RESEARCH In a one-of-a-kind study, Merck, ISB and Swedish Medical Center, along with several other research collaborators, have partnered to identify targets for medicines and vaccines for COVID-19. Learn more Brain Health RESEARCH ISB and our collaborative network of partners is pioneering a multimodal approach that combines personal data, lifestyle factors, cognitive training and systems medicine, and is rigorously testing these new approaches in clinical trials. This approach is critical to prevent, slow, and even reverse many neurological conditions before they become irreversible. Learn more Help us realize a new vision of health PHILANTHROPY We are a nonprofit scientific research organization dedicated to shifting the health care model from treating sickness to fostering wellness. You are committed to a better future, ISB is here to make that a reality. Learn More Latest News Coaching for Cognition in Alzheimer’s (COCOA) Clinical Trial Nearly Complete Posted on May 21, 2021 The multi-year Coaching for Cognition in Alzheimer’s (COCOA) clinical trial is nearly complete. The trial examined diet, exercise and cognitive training as possible non-pharmacological interventions to Alzheimer’s, with some trial members receiving telephonic coaching centered on stress, diet and exercise, as well as brain training focusing on brain speed and attention. Three Collaborative Projects Announced for ISB’s 2021 Innovator Award Program Posted on May 6, 2021 ISB has kicked off the fifth year of its Innovator Award Program by announcing three collaborative and cross-disciplinary projects. The program was created in 2017 to support early-career scientists working on high-risk, high-reward innovations, and champions interdisciplinary collaboration for non-faculty ISB researchers. Dr. Lee Hood Writes ‘Second Opinion’ Columns for Los Angeles Times Posted on April 29, 2021 ISB Co-founder Dr. Lee Hood is credited with coining the term “systems biology” and has been a longtime advocate of P4 medicine. Now, Hood has been selected by the Los Angeles Times to share his insights in a new weekly op-ed column, called Second Opinion. A New Approach to Alzheimer’s Disease Posted on April 21, 2021 The impact of Alzheimer’s Disease is staggering – 6 million Americans diagnosed, a financial toll of $600 billion annually, and no effective drug treatments. ISB Co-founder Dr. Lee Hood said the traditional approach isn’t working, and we need to think about it in brand new ways. David Sinclair On Why We Age — And Why We Don’t Have To Posted on April 16, 2021 Dr. David Sinclair, a Harvard Medical School professor and New York Times bestselling author, was the guest of honor for the ISB-Town Hall Science Series on Thursday. He joined genomics pioneer and ISB Co-founder Dr. Lee Hood for a conversation that covered the very latest in aging research. Personalized Nutrition and Your Gut Microbiome Posted on April 5, 2021 In ISB’s first-ever Research Roundtable event, Assistant Professor Dr. Sean Gibbons delivered a presentation titled “Gut-Check: Personalized Nutrition and Your Microbiome.” His talk covered a lot of ground, including recently published research showing how the health of our microbiomes can predict longevity, and how we can build and maintain a healthy gut microbiome. 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